II型コラーゲンの発現
Gene expression of type II collagen in a 16.5 d.p.c. mouse embryo
The lab members are involved in teaching Molecular Biology, Cell Biology, Biochemistry and related subjects for the students in the Faculty of Medicine.

Medical students Introductory course II, Tutorial course 2 (Biochemistry) and related tutorial course, and Experimental course.


Nursing students Biochemistry course
Masters course Basic Life Science course
Doctor course Matrix Biology course
Living organisms consist of numerous different types of cells. The cells must be hierarchically organized into tissues, organs and organs systems. In order to function as an organism, the extracellular matrix surrounds the cells and functions as the architecture of the body, such as in bone, cartilage skin and so on. However, recent advances in the fields of molecular biology, cell biology, and developmental biology have shown that the molecules in the extracellular matrix are actively involved in cell adhesion, proliferation, differentiation, induction and inhibition of angiogenesis. The goal of our research is to understand the roles of the molecules in the extracellular matrix, especially collagen.

The main projects are;
1) Transcriptional regulation of collagen genes
2)Elucidating the function of collagen molecules and their derived peptides
3)Basic research for elucidating the mechanism of fibrosis and its application for therapy