Original Article <ハラ チョ
2024ネン
  AUTHOR TITLE JOURNAL
1 Yoshimura K, Wei M, Kume S, Kurokawa T, Miyamoto S, Mizukami Y, Ono K  Detection and identification of factors in the atrium responsible for blood pressure regulation in patients with hypertension Heart and Vessels, doi.org/10.1007/s00380-024-02362-0
 
2023ネン
  AUTHOR TITLE JOURNAL
1 Wei M, Wang P, Zhu X, Morishima M, Liu Y, Zheng M, Liu G, Osanai H, Yoshimura K, Kume S, Kurokawa T, Ono K Electrophysiological evaluation of an anticancer drug gemcitabine on cardiotoxicity revealing down-regulation and modification of the activation gating properties in the human rapid delayed rectifier potassium channel. PLOS ONE, 18(2), 2023
doi: 10.1371/journal.pone.
0280656. eCollection
 
2022ネン
  AUTHOR TITLE JOURNAL
1 Ono K, Iwasaki Y, Akao M,  Ikeda T, et al. 2020 JCS/JHRS Guideline on Pharmacotherapy of Cardiac Arrhythmias Journal of Arrhythmia 2022; 00: 1-141. doi: 10.1002/joa3.12714
2 Wang Y, Morishima M, Ono K Protein kinase C regulates expression and function of the Cav3.2 T-type Ca²⁺ channel during maturation of neonatal rat cardiomyocyte Membranes 12(7), 686, 2022 doi.org/10.3390/membranes
12070686 
3 森島真幸, 岩田英理子, 宮本伸二, 小野克重 心房細動患者の心房筋における脳性ナトリウム利尿ペプチドとmiRNA-30dの発現の意義と心機能制御の可能性の検討 日本ニホン病態ビョウタイ生理セイリ学会ガッカイ雑誌ザッシ
31(1):61-68, 2022
4 Liu D, Zhan Y, Ono K, Yin Y, Wang L, Wei M, Ji L, Liu M, Liu G, Zhou X, Zheng M Pharmacological activation of estrogenic receptor G protein‑coupled receptor 30 attenuates angiotensin II‑induced atrial fbrosis in ovariectomized mice by modulating TGF‑β1/smad pathway Molecular Biology Reports, doi:10.1007/s11033-022-07444-8
5 Ono K, Iwasaki Y, Akao M,  Ikeda T, Ishii K, et al. 2020 JCS/JHRS Guideline on Pharmacotherapy of Cardiac Arrhythmias (statement) Circ J, doi: 10.1253/circj.CJ-20-1212
6 Zheng M, You D, Qiao Q, Ono K, Wei M, Tan W, Wang C, Liu Y, Liu G MiR-223-3p inhibit the progression of atherosclerosis via down-regulating the activation of MEK1/ERK1/2 in macrophages Aging ,14(4): 1865-1878, 2022, doi: 10.18632/aging.203908
 
2021ネン
  AUTHOR TITLE JOURNAL
1 Morishima M, Fujita T, Osagawa S, Kubota H, Ono K Enhanced BDNF actions following acute hypoxia facilitate HIF-1α-dependent upregulation of Cav3-T-type Ca²⁺ channels in rat cardiomyocytes Membranes 11: 470, 2021   doi.org/10.3390/membranes
11070470 
2 Wang P, Wei M, Zhu X, Liu Y, Yoshimura K, Zheng M, Liu G, Kume S, Morishima M, Kurokawa T, Ono K Nitric oxide down-regulates voltage-gated Na⁺ channel in cardiomyocytes possibly through S-nitrosylation-mediated signaling Scientific Reports 11: 11273, 2021       doi.org/10.1038/s41598-021-90840-0
3 Liu YS, Wei M, Wang L, Liu G, Ma GP, Ono K, Cao ZL, Yang M, Zheng MQ The impact of subclinical hypothyroidism on long-term outcomes in older patients undergoing percutaneous coronary intervention BMC Endocr Disord 2021 Mar 5; 21(1):43. doi.org/10.1186/s12902-021-00702-z
4 Morishima M,  Ono K Serum microRNA-30d is a sensitive biomarker for angiotensin II-induced cardiovascular complications in rats Heart and Vessels, 36(10), 1597-1606            doi.org/10.1007/s00380-021-01853-8
5 Morishima M, Tahara S, Wang Y, Ono K Oxytocin down-regulates the Cav1.2 L-type Ca²⁺ channel via Gi/cAMP/PKA/CREB signaling pathway in cardiomyocytes Membranes 11: 234, 2021      doi.org/10.3390/membranes
11040234
6 Wang P, Zhu X, Wei M, Liu Y, Yoshimura K, Zheng M, Liu G, Kume S, Kurokawa T, Ono K Disruption of asparagine-linked glycosylation to rescue and alter gating of the Nav1.5-Na⁺ channel Heart and Vessels 36: 589-596, 2021 doi.org/10.1007/s00380-020-01736-4                            
7 Suzuki R, Morishima M, Nakada C, Miyamoto S, Ono K Manifestations of gene expression profiles in human right atrial myocardium caused by mechanical stretch Heart and Vessels 36: 577-588, 2021 doi.org/10.1007/s00380-020-01724-8
2020ネン
  AUTHOR TITLE JOURNAL
1 Zheng M, Kang L, Uchino T, Liu G, Wang Y, Ono K Mitogen-activated protein kinase p38 modulates pacemaker ion channels differentiation in P19-derived pluripotent cells J Physiol Sci 70:39, 2020          doi:10.1186/s12576-020-00766-x 
2 Uchiyama M, Nakao A, Kurita Y, Fukushi I, Takeda K, Numata T, Tran NH, Sawamura S, Ebert M, Kurokawa T, Sakaguchi R, Stokes AJ, Takahashi N, Okada Y, Mori Y O2-Dependent Protein Internalization Underlies Astrocytic Sensing of Acute Hypoxia by Restricting Multimodal TRPA1 Channel Responses Curr Biol 17: 3378-3396.e7, 2020           doi:10.1016/j.cub.2020.06047
3 Wang Y, Morishima M, Li D, Takahashi N, Saikawa T, Nattel S, Ono K Binge alcohol exposure triggers atrial fibrillation through T-type Ca²⁺ channel upregulation via PKC/GSK3β/NFAT signaling –An experimental account of holiday heart syndrome– Circulation Journal 84:1931-1940, 2020 doi:10.1253/circj.CJ-20-0288                            
4 Shimaoka T, Wang Y, Morishima M, Miyamoto S, Ono K Magnesium Deficiency Causes Transcriptional Down-Regulation of Kir2.1 and Kv4.2 Channels in Cardiomyocytes Resulting in QT Interval Prolongation Circulation Journal 84:1244-1253, 2020                            doi:10.1253/circj.CJ-20-0310
5 森島真幸, 藤田崇史, 小野克重 脳由来神経栄養因子BDNFの心臓における発現と低酸素病態下での機能 近畿大学農学部紀要 第53号: 11〜23 (2020)
6 Tanaka M, Hayakawa K, Ogawa N, Kurokawa T, Kitanishi K, Ite K, Matsui T, Mori Y, Unno M  Structure determination of the human TRPV1 ankyrin-repeat domain under nonreducing conditions. Acta Crystallogr F Struct Biol Commun 76(Pt 3):130-137, 2020               doi:10.1107/s2053230x2000
1533
7 Jouraku A, Kuwazaki S, Miyamoto K, Uchiyama M, Kurokawa T, Mori E, Mori MX, Mori Y, Sonoda S Ryanodine receptor mutations (G4946E and I4790K) differentially responsible for diamide insecticide resistance in diamondback moth, Plutella xylostella L Insect Biochem Mol Biol 118:103308, 2020         doi:10.1016/j.ibmb.2019.1033
08
8 Uchino T, Zheng M, Wang Y, Ono K Cardiac specific transcription factor Csx/Nkx2.5 regulates transient-outward K+ channel expression in pluripotent P19 cell-derived cardiomyocytes J Physiol Sci 70:20, 2020                           doi:10.1186/s12576-020-00748-z
2019ネン
  AUTHOR TITLE JOURNAL
1 Horton JS, Shiraishi T, Alfulaij N, Small-Howard AL , Turner HC, Kurokawa T, Mori Y,  Stokes AJ TRPV1 is a component of the atrial natriuretic signaling complex, and using orally delivered antagonists, presents a valid therapeutic target in the longitudinal reversal and treatment of cardiac hypertrophy and heart failure. Channels (Austin)       
13(1): 1-16, 2019
2 Umeda R, Takanari H, Ogata K, Matsumoto S, Kitano T, Ono K, Tokumaru O Direct free radical scavenging effects of water-soluble HMG-CoA reductase inhibitors Journal of Clinical Biochemistry and Nutrition 64(1):20-26, 2019
3 Liu  Y,Wang Pu, Ma F, Zheng M, Liu G, Kume S, Kurokawa T, Ono K Asparagine-linked glycosylation modifies current density and voltage-dependent gating properties of Cav3.1-T-type Ca²⁺ channel   J Physiol Sci                            69:335-343, 2019
4 Liu Y, Iwano T,Ma F, Wang P, Wang Y, Zheng M, Liu G, Ono K Short- and long-term roles of phosphatidylinositol 4,5-bisphosphate PIP2 on Cav3.1- and Cav3.2-T-type calcium channel current Pathophysiology 26: 31-38, 2019
2018ネン
  AUTHOR TITLE JOURNAL
1 Masuda K, Takanari H, Morishima M, Ma F, Wang Y, Takahashi N, Ono K Testosterone-mediated upregulation of delayed rectifier potassium channel in cardiomyocytes causesabbreviation of QT intervals in rats J Physiol Sci
68(6):759-767, 2018
2016ネン
  AUTHOR TITLE JOURNAL
1 Morishima M, Iwata E, Nakada C, Tsukamoto Y, Takanari H, Miyamoto S, Moriyama M, Ono K Atrial fibrillation-mediated up-regulation of miR-30d regulates myocardial electrical remodeling of G-protein-gated K+ channel, IK.Ach Circulation Journal
80(6): 1346-5522, 2016
2 Ma F, Takanari H, Masuda K, Morishima M, Ono K Short- and long-term inhibition of cardiac inward-rectifier potassium channel current by an antiarrhythmic drug bepridil Heart Vessels
31(7): 1176-84, 2016
2015ネン
  AUTHOR TITLE JOURNAL
1 Shimaoka T, Wang Y, Morishima M, Miyamoto S, Ono K Hypomagnesemic down-regulation of L-type Ca2+ channel in cardiomyocyte as an arrhythmogenic substrate in rats Pathophysiology
22: 87-93, 2015
2 森島真幸モリシマ ヒト心房細動シンボウサイドウ心筋シンキンにおいて過剰カジョウ発現ハツゲンするmicroRNAの機能的キノウテキ意義イギ解析カイセキ 日本ニホン病態ビョウタイ生理セイリ学会ガッカイ雑誌ザッシ
24(3): 34-39, 2015
2014ネン
  AUTHOR TITLE JOURNAL
1 Kawano Y, Tamura A, Ono K,
Kadota J
Association between obstructive sleep apnea and premature supraventricular contractions Journal of Cardiology
63: 69–72, 2014
2013ネン
  AUTHOR TITLE JOURNAL
1 Uchino T, Isomoto  S, Noguchi T, Ono K Window current through the T-type Ca2+ channel triggers the mechanism for cellular apoptosis via mitochondrial pathways Heart Vessels 
28(5): 658-666, 2013
2 Nakano S, Ikebe E, Tsukamoto Y, Wang Y, Matsumoto T, Mitsui T, Yahiro T, Inoue K, Kawazato H, Yasuda A, Ito K, Yokoyama S, Takahashi N, Hori M, Shimada T, Moriyama M, Kubota T, Ono K, Fujibuchi W, Jeang K T, Iha H, Nishizono A Commensal microbiota contributes to chronic
endocarditis in TAX1BP1 deficient mice
PLOS ONE
8(9): e73205, 1-12, 2013
2012ネン
  AUTHOR TITLE JOURNAL
1 Sanyal SN*, Wada T*, Yamabe M, Anai H, Miyamoto S, Shimada T, Ono K Cardiac autonomic nerve abnormalities in chronic heart failure are associated with presynaptic vagal nerve degeneration Pathophysiology
19(4): 253-260, 2012
(*Equally Contributed
  1st author)
2 Sanyal SN*, Wada T*, Yamabe M, Anai H, Miyamoto S, Shimada T, Ono K Synaptic degradation of cardiac autonomic nerves
in streptozotocin-induced diabetic rats
Pathophysiology
19(4): 299-307, 2012
(*Equally Contributed
  1st author)
2010ネン
  AUTHOR TITLE JOURNAL
1 Zheng M, Wang Y, Kang L, Shimaoka T, Marni F, Ono K Intracellular Ca2+- and PKC-dependent upregulation of T-type Ca2+ channels in LPC-stimulated cardiomyocytes J Mol Cell Cardiol
48(1): 131-139, 2010
2 Hattori A, Mawatari K, Tsuzuki S, Yoshioka E, Toda S, Yoshida M, Yasui S, Furukawa H, Morishima M, Ono K, Ohnishi T, Nakano M, Harada N, Takahashi A, Nakaya Y b-adrenergic-AMPK pathway phosphorylates acetyl-CoA carboxylase in a high-epinephrine rat model, SPORTS Obesity
18(1): 45-54, 2010
3 Morishima M, Tahara S, Wang Y,  Kaku T, Ono K Nonapeptide hormones oxytocin and vasopressin distinctly regulate CaV1.2 L-type calcium channel expression in cardiomyocytes J Arrhythmia
26(2): 111–118, 2010
4 Srisawat R, Komalamisra N,Eshita Y,Zheng M,Ono K, Itoh T.Q,Matsumoto A,Petmitr S,Rongsriyam Y Point mutations in domain II of the voltage-gated sodium channel gene in deltamethrin-resistant Aedes aegypti (Diptera: Culicidae) Appl Entomol Zool, 45         ; 275-282, 2010.
2009ネン
  AUTHOR TITLE JOURNAL
1 Marni F, Wang Y, Morishima M, Shimaoka T, Uchino T, Zheng M-Q, Kaku T, Ono K 17b-estradiol modulates expression of low-voltage-activated CaV3.2 T-type calcium channel via ERKs pathway in cardiomyocytes Endocrinology   
150(2): 879-888, 2009 
2 Morishima M, Wang Y, Akiyoshi Y, Miyamoto S, Ono K Telmisartan, an angiotensin II type 1 receptor antagonist, attenuates T-type Ca2+ channel expression in neonatal rat cardiomyocytes Eur J Pharmacol 
609(1-3): 105-112, 2009
3 Kang L, Zheng M, Morishima M, Wang Y, Kaku T, Ono K Bepridil upregulates cardiac Na+ channel as a long-term effect by blunting proteasome signals through inhibition of calmodulin activity Br J Pharmacol
157(3): 404-414. 2009

4 Yamaguchi T, Yi SQ, Tanaka S, Ono K, Shimada T Ultrastructure and cytoarchitecture of Bachmann's bundle in the mammalian Heart J Arrhythmia    
25(1): 24-31, 2009
2008ネン
  AUTHOR TITLE JOURNAL
1 Uchino T*, Sanyal SN*, Yamabe M, Kaku T, Takebayashi S, Shimaoka T, Shimada T, Noguchi T, Ono K Rescue of Pulmonary Hypertension with an Oral Sulfonamide Antibiotic Sulfisoxazole by Endothelin Recepter Antagonistic Actions Hypertens Res
2008 Sep;31(9): 1781-90
(*Equally Contributed
  1st authors)
 
2007ネン
  AUTHOR TITLE JOURNAL
1 Cronk LB, Ye B, Kaku T, Tester DJ, Vatta M, Makielski JC, Acerman MJ Novel mechanism for sudden infant death syndrome: persistent late sodium current secondary to mutations in caveolin-3 Heart Rhythm
4(2): 161-6, 2007
2 Harada N, Kusuyama A, Morishima M, Okada K, Takahashi A, Nakaya Y Bezafibrate improves bacterial lipopolysaccharide-induced dyslipidemia and anorexia in rats Metabolism
56(4): 517-522, 2007
3 Wang Y, Morishima M, Zheng M, Uchino T, Mannen K, Takahashi A, Nakaya Y, Komuro I, Ono K Transcription factors Csx/Nkx2.5 and GATA4 distinctly regulate expression of Ca2+ channels in neonatal rat heart J Mol Cell Cardiol
42(6): 1045-1053, 2007
4 Yamabe M, Sanyal SN, Miyamoto S, Hadama T, Isomoto S, Ono K Three different bradycardic agents, zatebradine, diltiazem and propranolol, distinctly modify heart rate variability and QT-interval variability Pharmacology
80(4): 293-303, 2007
5 Suzuki S, Ohkusa T, Ono K, Sato T, Yoshida M, Yano M, Takebayashi S, Matsuzaki M Beneficial effects of the dual L- and T-type Ca2+ channel blocker efonidipine on cardiomyopathic hamsters Circ J
71(12): 1970-1976, 2007
6 Medeiros-Domingo A*, Kaku T*, Tester DJ, Iturralde-Torres P, Itty A, Ye B, Valdivia C, Ueda K, Canizales-Quinteros S, Tusié-Luna MT, Makielski JC, Ackerman MJ SCN4B-encoded sodium channel b4 subunit in congenital long-QT syndrome Circulation
116(2): 134-142, 2007
(*Equally Contributed
  1st author)
       
2006ネン    
  AUTHOR TITLE JOURNAL
1 Zheng M, Uchino T, Kaku T, Kang L, Wang Y, Takebayashi S, Ono K Lysophosphatidylcholine augments CaV3.2 but not CaV3.1 T-type Ca2+ channel current expressed in HEK-293 cells Pharmacology
76(4): 192-200, 2006 
2 Yamashita N, Kaku T, Uchino T, Isomoto S, Yoshimatsu H, Ono K Short- and long-term amiodarone treatments regulate CaV3.2 low-voltage-activated T-type Ca2+ channel through distinct mechanisms Mol Pharmacol
69(5): 1684-1691, 2006  
3 Takebayashi T, Li Y, Kaku T, Inagaki S, Hashimoto Y, Kimura K, Miyamoto S, Hadama T, Ono K Remodeling excitation-contraction coupling of hypertrophied ventricular myocytes is dependent on T-type calcium channels expression  Biochem Biophys Res Com
345(2): 766-773, 2006
4 Lee TS, Karl R, Moosmang S, Lenhardt P, Klugbauer N, Hofmann F, Kleppisch T, Welling A Calmodulin kinase II is involved in voltage-dependent facilitation of the L-type CaV1.2 calcium channel: Identification of the phosphorylation sites J Biol Chem
281(35): 25560-25567, 2006  
5 Isomoto S, Kawakami A, Arakaki T, Yamashita S, Yano K, Ono K
Effects of antiarrhythmic drugs on apoptotic pathways in H9c2 cardiac cells J Pharmacol Sci
101(4): 318-324, 2006 
6 Lee TS, Kaku T, Takebayashi S, Uchino T, Miyamoto S, Hadama T, Perez-Reyes E, Ono K Actions of mibefradil, efonidipine and nifedipine block of recombinant T- and L-type Ca channels with distinct inhibitory mechanisms Pharmacology
78(1): 11-20, 2006 
7 Lee TS, Ono K, Miyamoto S, Hadama T, Arita M Distinction between steady-state inactivation and voltage-dependent facilitation in L-type Ca2+ channel a1c and a1c/b subunits. J UOEH
28(3): 277-286, 2006
8 Morishima M, Harada N, Hara S, Sano A, Seno H, Takahashi A, Morita Y, Nakaya Y Monoamine oxidase A activity and norepinephrine level in hippocampus determine hyperwheel running in SPORTS rats Neuropsychopharmacol
31(12): 2627-2638, 2006  
9 Chikahisa S, Sei H, Morishima M, Sano A, Kitaoka K, Nakaya Y, Morita Y Exposure to music in the perinatal period enhances learning performance and alters BDNF/TrkB signaling in mice as adults Behav Brain Res
169(2): 312-9, 2006 
       
2005ネン    
  AUTHOR TITLE  
1 Centurión OA, Shimizu A, Isomoto S, Konoe A, Karibara M, Hayano M, Yano K Influence of advancing age on fractionated right atrial endocardial electrograms Am J Cardiol
96(2): 239-242, 2005
2 Isomoto S, Centurión  OA, Shibata R, Doi Y, Fukae S, Nakao K, Komiya N, Yano K The effects of aging on the refractoriness and conduction of the atrium in patients with lone paroxysmal atrial fibrillation resealed with programmed atrial stimulation Rev Soc Parag Cardiol
1: 25-30, 2005
3 Uchino T, Lee TS, Kaku T, Yamashita N, Noguchi T, Ono K Voltage-dependent and frequency-independent inhibition of recombinant CaV3.2 T-type Ca2+ channel by bepridil Pharmacology
74(4): 174-181, 2005
4 鄭明奇, 内納智子, 竹林聡, 賀来俊彦, 王岩, 小野克重 P19CL6細胞の心筋細胞への分化はp38-MAPKを介するGATA4発現に依存する Jpn J Electrocardiol
25(6): 495-501, 2005
2004ネン    
  AUTHOR TITLE JOURNAL
1 Kaku T, Ozaki H, Ishii S, Shimizu T, Ono K Platelet activating factor affects intracellular calcium concentration by modulating L-type calcium channel Adv Electrocardiol
suppl
31: 92-96, 2004
2 Miyamoto S, Hadama T, Anai H, Sako H, Wada T, Iwata E, Nakayama K, Takeoka H, Ono K Denervation and reinnervation of the heart after aortic surgery, estimated by 123I-metaiodobenzylguanidine scintigraphy Surg Today
34(3), 226-230, 2004
3 Isomoto S, Kawakami A, Ohtsuru A, Yamashita S, Yano K Antiarrhythmic amiodarone mediates apoptotic cell death of HepG2 hepatoblastoma cells through the mitochondrial pathway Acta Med Nagasaki
49: 13-17, 2004
4 Wegener JW, Schulla V, Lee TS, Koller A, Feil S, Feil R, Kleppisch T, Klugbauer N, Moosmang S, Welling A, Hofmann F An essential role of CaV1.2 L-type calcium channel for urinary bladder function FASEB J
18(10): 1159-1161, 2004
5 Isomoto S, Shimizu A Different electrophysiological alterations in patients with paroxysmal atrial fibrillation depending on the underlying disorder:  Clinical implications for future developments of novel antiarrhythmic drugs Revista de la Sociedad Paraguaya de Cardiología
2(2): 107-112, 2004
6 Isomoto S, Centurión OA, Shibata R, Doi Y, Fukae S, Nakao K, Komiya N, Yano K Patients with paroxysmal atrial fibrillation exhibit an electrophysiological diversity of the atrium in conjunction with their complication status Revista de la Sociedad Paraguaya de Cardiología
2(2): 119-124, 2004
2003ネン    
  AUTHOR TITLE  
1 Kaku T, Lee TA, Arita M, Hadama T and Ono K The gating and conductance properties of CaV3.2 low-voltage-activated T-type calcium channels Jpn J Physiol
53(3): 165-172, 2003
2002ネン    
  AUTHOR TITLE JOURNAL
1 Sanyal SN, Arita M, Ono K  Inhomogeneous derangement of cardiac autonomic nerve control in diabetic rats Circ J
66(3): 283-288, 2002
2 Sanyal SN, Ono K  Derangement of autonomic nerve control in rat with right ventricular failure Pathophysiology
8(3): 197-203, 2002
3 Valdivia CR, Ackerman MJ, Tester DJ, Wada T, McCormack J, Ye B, Makielski JC  A novel SCN5A arrhythmia mutation, M1766L, with expression defect rescued by mexiletine Cardiovasc Res 
55(2): 279-289, 2002
4 Chutkow WA, Pu J, Wheeler MT, Wada T, Makielski JC, Burant CF, McNally EM Episodic coronary artery vasospasm and hypertension develop in the absence of Sur2 K(ATP) channels J Clin Invest
110(2): 203-208, 2002
 
2001ネン    
  AUTHOR TITLE JOURNAL
1  Ito K, Sato T, Arita M  Protein kinase C isoform-dependent modulation of ATP-sensitive K+ channels during reoxygenation in guinea-pig ventricular myocytes J Physiol 
532: 165-174, 2001
2 李泰成, 小野克重, 賀来俊彦, 有田 眞 T型Ca2+チャネル(a1H)電流のmibefradilによる抑制 Jpn J Electrocardiol  
21(3): 308-315, 2001
Lee TS, Ono K, Hadama T, Uchida Y, Arita M Roles of a1 and a1/b subunits derived from cardiac L-type Ca2+ channels on voltage-dependent facilitation mechanisms Jpn J Physiol  
51(3): 337-344, 2001
4 Li Y, Sato T Dual signaling via protein kinase C and phosphatidylinositol 3'-kinase/Akt contributes to bradykinin B2 receptor-induced cardioprotection in guinea pig hearts J Mol Cell Cardiol
33(11): 2047-2053, 2001
2000ネン    
  AUTHOR TITLE JOURNAL
1 Hu H, Janecki M, Sato T, O'Rourke B, Marbán E  Modulation of expressed cardiac ATP-sensitive potassium channels by protein kinase C Analytical Pharmacology
1: 40-47, 2000
2 Ono K,Kaku T,Makita N,Kitabatake A,Arita M Selective block of late currents in the ΔKPQ Na+ channel mutant by pilsicainide and lidocaine with distinct mechanisms Mol Pharmacol     
57(2): 392-400, 2000
3 Ito K,Shigematsu S,Sato T,Abe T,Li Y,Arita M JTV-519, a novel cardioprotective agen, improves the contractile recovery after ischaemia-reperfusion in coronary perfused guinea-pig ventricular muscles Br J Pharmacol  
130(4): 767-776, 2000
4 Kiriyama K,Kiyosue T,Wang J C,Dohi K,Arita M Effects of JTV-519, a novel anti-ischaemic drug, on the delayed rectifier K+ current in guinea-pig ventricular myocytes Naunyn-Schmiedeberg's Arch Pharmacol 
361(6): 646-653, 2000
5 Sasaki N, Sato T, Ohler A, O’Rourke B, Marbán E Activation of mitochondrial ATP-dependent potassium channels by nitric oxide Circulation    
101(4): 439-445, 2000
6 Sato T, Sasaki N, O’Rourke B, Marbán E Adenosine primes the opening of mitochondrial ATP-sensitive potassium channels: a key step in ischemic preconditioning? Circulation         
102(7): 800-805, 2000  
7 Sato T, Sasaki N, Seharaseyon J, O’Rourke B, Marbán E Selective pharmacological agents implicate mitochondrial but not sarcolemmal KATP channels in ischemic cardioprotection Circulation      
101(20): 2418-2423, 2000  
8 Sato T, Sasaki N, O’Rourke B, Marbán E Nicorandil, a potent cardioprotective agent, acts by opening mitochondrial ATP-dependent potassium channels J Am Coll Cardiol
35(2): 514-518, 2000 
9 Saikawa T, Arita M, Yamaguchi K, Ito M Hypoglycemic effect of cibenzoline in patients with abnormal glucose tolerance and frequent ventricular arrhythmias Cardiovasc Drug  Ther
14(6): 665-669, 2000
10 Ono K, Lee T-A, Kaku T, Arita M Pharmacological properties of the human cardiac cloned T-type calcium channel Jpn J Electrocardiol
20: S-3-109 – S-3-112, 2000