臨床薬理学
Clinical Pharmacology and Therapeutics
整理番号 論文の種類 著者名 論文タイトル 誌名、書名等 巻号ページ doi
2257001 原著 Doi T. Hojo H. Ohba S. Obayashi K. Endo M. Ishizaki T. Katoh A. Kouji H. Involvement of activator protein-1 family members in β-catenin and p300 association on the genome of PANC-1 cells Heliyon 2022, 8, e08890 2022  
2257002 原著 Kami D. Ishizaki T. Taya T. Katoh A. Kouji H. Gojo S. A novel mRNA decay inhibitor abolishes pathophysiological cellular transition Cell Death Discovery 2022, 278 1-9 2022 10.1038/s41420-022-01076-4
2257003 症例報告 Hayashi K, Ito T, Hachiya K, Ichihashi T, Sakurai Y, Murakami Y, Kamiya S, Saito J, Asano M, Seo Y. Sudden Cardiac Arrest Due to Spontaneous Coronary Artery Rupture - A Case Report with a Diagnostic Challenge - Internal Medicne 2022 Volume 61 Issue 22 Pages 3369-3372 2022 10.2169/internalmedicine.9369-22
2257004 原著 Nozawa A, Fujino A, Yuzuriha S, Suenobu S, Kato A, Shimizu F, Aramaki-Hattori N, Kuniyeda K, Sakaguchi K, Ohnishi H, Aoki Y, Ozeki M. Comprehensive targeted next-generation sequeincing in ptients with slow-flow vascular malformations J. Human Genet. 2022 Sep 29. Online ahead of print 2022 10.1038/s10038-022-01081-6
2257005 原著 Orito Y, Otani N, Matsumoto Y, Fujimoto K, Oshima N, Maas BM, Caro L, Aliprantis AO, Cox KS, Tokumaru O, Kodama M, Kudo H, Imai H, Uemura N. A Phase 1 Study to Evaluate Safety, Pharmacokinetics, and Pharmacodynamics of Respiratory Syncytial Virus (RSV) Neutralizing Monoclonal Antibody MK-1654 in Healthy Japanese Adults.  Clinical and translational science 15(7) 1753-1763 2022  
2257006 総説 Otani N, Ouchi M,
Misawa K, Hisatome I, Anzai N.
Hypouricemia and Urate Transporters Biomedicines Biomedicines 2022, 10,
652. https://doi.org/10.3390/
biomedicines10030652
2022  
2257007 原著 Hirayama K, Kuranari M, Wakuda H, Otani N, Imai H, Uemura N. Scientific misconduct in sponsored clinical trials in Japan – Published cases are the “tip of the iceberg” Translational and Regulatory Sciences 4(2): 30-36 2022  
2257008 原著 Umegawa Y, Yamamoto T, Dixit M, Funahashi K, Seo S, Nakagawa Y, Suzuki T, Matsuoka S, Tsuchikawa H, Hanashima S, Oishi T, Matsumori N, Shinoda W, Murata M. Amphotericin B assembles into seven-molecule ion channels: An NMR and molecular dynamics study Sci Adv 2022 Jun 17;8(24):eabo2658. 2022 10.1126/sciadv.abo2658.
2257009 原著 Sugiyama S, Matsuoka D, Hara T, Sonoyama M, Matsuoka S, Murata M. Experimental and theoretical investigations into the mechanism of interactions between membrane-bound fatty acids and their binding protein: A model system to investigate the behavior of lipid acyl chains in contact with proteins Chem Phys Lipids 2022 Sep;247:105227. 2022 10.1016/j.chemphyslip.2022.105227
2257010 原著 Nishida M, Terabayashi T, Matsuoka S, Okuma T, Adachi S, Tomo T, Kawano M, Tanaka K, Tsumura H, Anai H, Ishizaki T, Nishida Y, Hanada K. Mechanism of action of non-camptothecin inhibitor Genz-644282 in topoisomerase I inhibition Commun Biol 2022 Sep 16;5(1):982. 2022 10.1038/s42003-022-03920-w.
2257011 原著 Kinoshita T, Shinoda M, Nishizaki Y, Shiraki K, Hirai Y, Kichikawa Y, Tsushima K, Sinkai M, Komura N, Yoshida K, Kido Y, Kakeya H, Uemura N, Kadota J.  A multicenter, double-blind, randomized, parallel-group, placebo-controlled study to evaluate the efficacy and safety of camostat mesilate in patients with COVID-19 (CANDLE study). BMC Med. 2022 Sep 27;20(1):342. 2022 10.1186/s12916-022-02518-7.
2257012 原著 Nakamura K, Fujimoto K, Hasegawa C, Aoki I, Yoshitsugu H, Ugai H, Yatsuzuka N, Tanaka Y, Furihata K, Maas BM, Wickremasingha PK, Duncan KE, Iwamoto M, Stoch SA, Uemura N.  A phase I, randomized, placebo-controlled study of molnupiravir in healthy Japanese to support special approval in Japan to treat COVID-19. Clin Transl Sci. 2022 Nov;15(11):2697-2708.
Epub 2022 Sep 23.
2022 10.1111/cts.13395.
2257013 原著 Imai H, Hashimoto S, Ninomiya R, Luo J, Wakuda H, Otani N, Inoue G, Amagishi H, Uemura N.  Pharmacokinetics of lanoconazole in human skin after repeated topical application. J Dermatol. 2022 Nov;49(11):1118-1123.
Epub 2022 Jul 10.
2022 10.1111/1346-8138.16515.
2257014 原著 Nakagama Y, Rodriguez-Funes MV, Dominguez R, Candray-Medina KS, Uemura N, Tshibangu-Kabamba E, Nitahara Y, Kaku N, Kaneko A, Kido Y.  Cumulative seroprevalence among healthcare workers after the first wave of the COVID-19 pandemic in El Salvador, Central America. Clin Microbiol Infect. 2022 Nov;28(11):1508-1510.
Epub 2022 Jun 28.
2022 10.1016/j.cmi.2022.06.020.
2257015 原著 Orito Y, Otani N, Matsumoto Y, Fujimoto K, Oshima N, Maas BM, Caro L, Aliprantis AO, Cox KS, Tokumaru O, Kodama M, Kudo H, Imai H, Uemura N.  A phase I study to evaluate safety, pharmacokinetics, and pharmacodynamics of respiratory syncytial virus neutralizing monoclonal antibody MK-1654 in healthy Japanese adults. Clin Transl Sci.  2022 Jul;15(7):1753-1763.
Epub 2022 May 17.
2022 10.1111/cts.13290.
2257016 原著 Kinoshita T, Shinoda M, Nishizaki Y, Shiraki K, Hirai Y, Kichikawa Y, Tsushima K, Shinkai M, Komura N, Yoshida K, Kido Y, Kakeya H, Uemura N, Kadota J. Correction: A multicenter, double-blind, randomized, parallel-group, placebo-controlled study to evaluate the efficacy and safety of camostat mesilate in patients with COVID-19 (CANDLE study) BMC Med 20(1)478 2022 10.1186/s12916-022-02695-5